Tyrosine phosphatase Shp2 accelerated the progression of dilated cardiomyopathy via upregulating NF-κB/Src/FAK signaling induced ROS and mitophagy.

Sci Rep · 2025 · PMC12343947 · PMID 40796569

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a decreasing trendno p-value reported

And the relative fluorescence intensity of PINK in Shp2 f/f LysM Cre +Doxorubicin + VAS2870 group showed a decreasing trend, but no significant difference was observed compared with Shp2 f/f +Doxorubicin + VAS2870 group ( P > 0.05) (Fig. 5 B).

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