Lifestyle, genetic risk, plasma pTau217, and incident cognitive impairment in WRAP.

Alzheimers Dement · 2025 · PMC12344448 · PMID 40799136

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marginally significantno p-value reported

Analysis of the secondary outcome (ICI defined using longitudinal norms; n = 304 (27.9%) impaired) no longer showed a difference between moderate and low lifestyle risk, and only a marginally significant increase in risk of ICI for those with high lifestyle risk (Figure S2 and Table S3 ).

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