Enhanced NIR-II Nanoparticle Probe for PSMA-Targeted Molecular Imaging and Prostate Cancer Diagnosis.

In relation to Gleason scores, PSMA levels demonstrated an increasing trend with higher scores, but at a Gleason score as high as 10, PSMA expression shows no statistically significant difference compared to that in normal controls ( Supplementary Figure 1d ), which reflects similarities with the trend of low PSMA expression in NEPC and DNPC ( Figure 1b and 1c ).

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