Barely Significant
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Neoadjuvant Treatment for Locally Advanced Rectal Cancer: Current Status and Future Directions.

Cancers (Basel) · 2025 · PMC12346518 · PMID 40805234

Europe PMCDOI
1
hedged sentence
0.0500
closest p · 1.0× alpha
0.0500
boldest claim

The sentences

a favorable trendp = 0.05actually significant
A meta-analysis incorporating these two RCTs demonstrated that LC-CRT significantly improved pCR compared with SC-RT (risk ratio [RR] = 0.15, 95% CI 0.08–0.28; p < 0.00001) and showed a favorable trend toward greater tumor down-staging (RR = 0.61, 95% CI 0.37–1.01; p = 0.05) [ 56 ].

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