The global burden of osteoarthritis hand: lessons from the Global Burden of Disease Study 1990-2021.

Front Med (Lausanne) · 2025 · PMC12350485 · PMID 40823563

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a worrying trendno p-value reported

A worrying trend is the earlier onset of HOA, with individuals under 55 increasingly affected, leading to prolonged disability, joint surgeries, and estimated annual productivity losses exceeding US$106.8 billion in some economies ( 8 ).

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