Total GSLs, GM3, and GM2 showed a borderline significant upward trend (Fig. 3 A), while other detected species in iIAs, including Lac, GM1a, GD3, and GU4.79–4.82 did not exhibit changes (Fig. 3 A).
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Lysosomal free sialic acid storage disorder iPSC-derived neural cells display altered glycosphingolipid metabolism.
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