Notably, the distribution of motor subgroups differed markedly across control, prodromal AD, and AD dementia groups, demonstrating an increasing trend in motor symptom severity (no/subtle, MPS, overt parkinsonism) in accordance with cognitive decline ( p for trend < 0.001) (Figure 1B ).
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Neural basis of motor symptoms in Alzheimer's disease: role of regional tau burden and cognition.
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