Barely Significant
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Global, regional, and national burden of knee osteoarthritis: findings from the Global Burden of Disease study 2021 and projections to 2045.

J Orthop Surg Res · 2025 · PMC12351899 · PMID 40804406

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a decreasing trendno p-value reported
It is also noteworthy that the KOA burden in the United States is showing a decreasing trend, possibly due to widespread health interventions [ 3 ].

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