Global, regional, and national burden of non-rheumatic valvular heart disease and Its projections to 2035: comprehensive analysis of the global burden of disease study 2019.

Front Cardiovasc Med · 2025 · PMC12354459 · PMID 40822005

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a decreasing trendno p-value reported

Trends of ASIR, ASPR, ASMR, and ASDR of NRVHD globally from 1990 to 2019 Overall, ASIR (AAPC = 0.27, p < 0.001) and ASPR (AAPC = 0.09, p < 0.001) of NRVHD showed an upward trend according to the Joinpoint analysis, the ASMR (AAPC = −0.36, p < 0.001) and ASDR (AAPC = −0.73, p < 0.001) showed a decreasing trend.

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