HEK293T cells with net reductive TCA due to loss of SDHAF2 and antimycin A treatment, as well as UQCRC1 KO and UQCRC1/SDHAF2 DKO , showed a slight trend toward a lower ubiquinol to ubiquinone ratio relative to conditions where SDHAF2 is present; however, the change in ratio was not significant (compare red solid/hatched to purple solid/hatched in Fig. 6A ).
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