Conversely, Figure 1c shows a highly significant CD8 + CD44 hi CD127(-/lo) T cell population contraction after PPD stimulation (left panel), but again no sex differences are evident (right panel).
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The Ability of Neonatal Mice to Develop Immunity to <i>Mycobacterium tuberculosis</i> Shows Sex Differences, with Females Displaying Evidence of an Enhanced Immune Response.
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With Mtb alone, there was a decrease in Tregs (CD4 + CD25 + Foxp3 + ) in male pups, and females also showed a decreasing trend, as one might predict ( Figure 5a ).