Therapeutic Potential of Adipose Mesenchymal Stem Cells for Synovial Regeneration: from In-Vitro Studies to Clinical Applications.

Stem Cell Rev Rep · 2025 · PMC12356737 · PMID 40493163

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highly significantno p-value reported

Their single center, randomized, double-blind, placebo-controlled, single ascending dose study showed significant within-group improvement in pain scores from baseline at all-time points for the PRG group, with highly significant improvements seen at months 3, 6, 9, and 12 compared to the marginal improvement in the placebo group [ 102 ].

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