Efficacy and Safety of Oral Spironolactone for Women With Acne Vulgaris: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials With Trial Sequential Analysis.

J Cosmet Dermatol · 2025 · PMC12359290 · PMID 40823723

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highly significantno p-value reported

This dosage showed a highly significant improvement in inflamed lesions, while having more adverse events [ 6 , 15 , 16 ].

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