Importantly, over the entire course of infection, NA-F2A-HA- and NA + HA-vaccinated mice were completely protected from severe morbidity and mortality with no noticeable weight loss, and NA-F2A-HA-vaccinated mice displayed a slight trend for faster weight gain ( Fig. 3H and I ).
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Development of DNA and mRNA-LNP vaccines against an H5N1 clade 2.3.4.4b influenza virus.
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