The finding that deposition could be targeted to either the middle turbinate region, or the inferior turbinate region/nasopharynx, by administering the aerosol in different head positions may be significant, since it is not clear if the nasopharynx is the only target site for immunization.
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Targeting aerosol delivery to regions of nasal-associated lymphoid tissue (NALT) in three dimensional models of human intranasal airways using the BiVax intranasal atomizer.
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