HEE-SegGAN: A holistically-nested edge enhanced GAN for pulmonary nodule segmentation.

PLoS One · 2025 · PMC12364326 · PMID 40828814

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highly significantno p-value reported

The introduction of an edge detection mechanism in HED-U-Net led to improved segmentation accuracy over U-Net, and the statistical difference between the two was found to be highly significant.

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