The Cerebral Lymphatic System: Function, Controversies, and Therapeutic Approaches for Central Nervous System Diseases.

Cell Mol Neurobiol · 2025 · PMC12364799 · PMID 40828342

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TBI induces both morphological and functional changes in MLVs, including increased expression of lymphatic vessel endothelial hyaluronan receptor 1 (Lyve-1), a significant increase in the number of endothelial loops and buds within the lymphatic system, and an overall trend toward increased lymphatic vessel diameter (Bolte et al. 2020 ).

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