The total indirect effect from Reading-PGS to Decoding showed a trend toward significance (β = 0.057, SE = 0.030; 90% CI = 0.005/0.106), with minimal changes in the percent of explained variance (28.1%) and no changes to the other observed indirect paths (Supplementary Table 4 —Supplementary Fig. 2 ).
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Mediational effects of reading-related intermediate phenotypes from polygenic scores to reading skills.
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