highly significantp < 0.0001
* p < 0.05 was considered statistically significant; ** p < 0.01, very significant; *** p < 0.001, highly significant; and **** p < 0.0001, extremely significant.
* p < 0.05 was considered statistically significant; ** p < 0.01, very significant; *** p < 0.001, highly significant; and **** p < 0.0001, extremely significant.