The development of FXR ligands, particularly nonsteroidal antagonists, is highly significant for dissecting and shedding light on the complex biological pathways under FXR control and for understanding the molecular‐level conformational changes of the receptor in its agonistic and antagonistic forms.
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The Role of Five-Membered Aromatic Rings Containing N and O in Modulating Bile Acid Receptors: An Overview.
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