Guidance for the design and analysis of cell-type-specific DNA methylation epidemiology studies.

Brief Bioinform · 2025 · PMC12368846 · PMID 40838785

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

may be significantno p-value reported

For regression models that include all data from all samples (allLR, MER, and CRR), depending on which cell type(s) a DMP affects, both or either of the main effect and interaction term may be significant, so both terms must be considered when assessing these methods.

also in 13,097 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.