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Elucidating the dynamic tumor microenvironment through deep transcriptomic analysis and therapeutic implication of MRE11 expression patterns in hepatocellular carcinoma.

Cancer Cell Int · 2025 · PMC12369108 · PMID 40841647

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Temporal trajectory analysis indicated MRE11 expression showed a decreasing trend over time, and the differential genes exhibited two opposite expression trends, further confirming MRE11 dynamic role in HCC (Fig. 5 D-E, Supplementary Fig. 6 I-J).

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