Barely Significant
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Impact of High Maximum Dose Constraints Within the Gross Tumor Volume on the Quality of Stereotactic Radiosurgery Plans Using Volumetric-Modulated Arcs for Brain Metastases.

Cureus · 2025 · PMC12370324 · PMID 40851724

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a favorable trendno p-value reported
The 55% and 60% groups showed a favorable trend in smaller prescription isodose volume spillage; however, no significance was observed in other evaluation metrics.

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