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Analyzing the global burden of 11 subtypes of congenital birth defects: trends, sociodemographic correlates, and outcomes from 1990 to 2021.

Ann Med · 2025 · PMC12372484 · PMID 40528359

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a decreasing trendno p-value reported
The prevalence of, mortality due to, and DALYs attributable to CBDs generally showed a decreasing trend globally, indicating improvements in child health conditions worldwide, particularly in the management and prevention of CBDs.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.