Barely Significant
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Iron overload exaggerates renal ischemia-reperfusion injury by promoting tubular cuproptosis via interrupting function of LIAS.

Redox Biol · 2025 · PMC12375214 · PMID 40753758

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a decreasing trendno p-value reported
Cells overexpressing ISCA1 exhibited reduced mortality upon FeCl 2 and ES-Cu treatment and cells overexpressing ISCA2 showed a decreasing trend in mortality, though without reaching statistical significance.

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