Barely Significant
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Cutaneous manifestations-associated with tuberous sclerosis complex and the use of topical rapamycin in the United States: a sub-analysis of an international survey of caregivers and patients.

Orphanet J Rare Dis · 2025 · PMC12379466 · PMID 40855504

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a decreasing trendno p-value reported
Self-reports by patients revealed a decreasing trend of topical rapamycin use with age; however, the n values were very low (Fig. 3 C).

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