Although we found little evidence to support that the major cannabinoids CBD and CBDA were enhanced by administrated as full spectrum products, there appears to be a numerical trend over 7 days on full spectrum CBDA absorption, therefore the “entourage effect” is not likely to be related to the major cannabinoid absorption, but rather to the minor components found in full spectrum products.
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Limited 12-hour pharmacokinetic assessment of CBD and CBDA isolates compared to their full-spectrum extracts in healthy adult beagles.
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