Barely Significant
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Methionine enkephalin upregulates the immune function of RAW264.7 cells to inhibit the infection of Nelson Bay orthoreoviruses.

Sci Rep · 2025 · PMC12381227 · PMID 40858872

Europe PMCDOI
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an increasing trendP < 0.05actually significant
In the differential analysis between NBV-MB control group and MENK-NBV-MB group, the levels of the genes IL6ST, TNFR2, CCL24, MHC I, MHC II, CD28, FOXO-1, and SYK in the macrophages of the MENK-NBV-MB group showed an increasing trend (P < 0.05), while the level of CYCD1 genes were downregulated (P < 0.05), as shown in Fig. 7 .

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