Among the 20 studies assessing alpha diversity, 3 reported statistically significant reductions in HNSCC patients [ 6 , 33 , 35 ], 7 observed a decreasing trend [ 16 , 25 , 27 , 30 , 31 , 32 , 34 ], and 10 found no significant differences [ 17 , 18 , 19 , 20 , 21 , 23 , 24 , 26 , 28 , 29 ].
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Oral Microbiome as a Biomarker and Therapeutic Target in Head and Neck Cancer: Current Insights and Future Directions.
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