Characteristics of Intestinal Barrier State and Immunoglobulin-Bound Fraction of Stool Microbiota in Advanced Melanoma Patients Undergoing Anti-PD-1 Therapy.

Int J Mol Sci · 2025 · PMC12387085 · PMID 40869383

Europe PMC DOI

hedged sentence

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

borderline significantp -value = 0.054so close (0.05 < p ≤ 0.1)

The baseline concentration of the biomarker higher than 212 μg·mL −1 was significantly associated with increased risk of disease progression (PFS HR 2.5 (1–6), p -value = 0.042, Figure 3 F), and there was a borderline significant association with increased risk of death (OS HR 2.6 (0.98–7.1), p -value = 0.054, Figure 3 H).

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