The consolidated data compellingly attest to a marked diminution—by approximately 50%—of the proliferative activity of RA-FLSs, accompanied by a concurrent 2.6-fold increase in the frequency of apoptosis, whereas the impact on migratory potential is confined merely to a statistical trend.
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Pharmacological Inhibition of the PI3K/AKT/mTOR Pathway in Rheumatoid Arthritis Synoviocytes: A Systematic Review and Meta-Analysis (Preclinical).
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