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Perspectives on the History and Epidemiology of the Varicella Virus Vaccine and Future Challenges.

Pathogens · 2025 · PMC12389673 · PMID 40872323

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an increasing trendno p-value reported
While shingles in adults has continued to increase as chickenpox cases in children have decreased dramatically with the introduction of the varicella vaccine, the incidence of shingles has shown an increasing trend since the 1950s, long before the vaccine was introduced [ 109 ].

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