Stepwise approach to alzheimer's disease diagnosis in primary care using cognitive screening, risk factors, neuroimaging and plasma biomarkers.

In the subgroup with SCD, 25.0% were A+, and 5.3% were A + T+, compared to 14.8% and 3.8% among cognitively normal individuals, respectively suggesting a possible trend toward increased pathological burden in individuals with subjective complaints, although this should be interpreted cautiously due to the small sample size (Figure S4 ).

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