borderline significanceP =.051
There was substantial heterogeneity among the included studies ( I 2 =97.8%, τ 2 =0.91, P <.001; Figure S7 in Multimedia Appendix 1 ) and borderline significance for publication bias ( P =.051; Figure S7 in Multimedia Appendix 1 ), and no studies were found to be influential (Figure S8 in Multimedia Appendix 1 ).