Comparative analysis of CDR3 length-dependent patterns in VHHs.

Front Immunol · 2025 · PMC12394203 · PMID 40895531

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highly significantno p-value reported

Correlation analysis showed that VHHs with extended CDR3 displayed a positive correlation with CDR3 length only for the CDR1/CDR3 interaction, while VHHs with bent CDR3 showed highly significant positive correlation with CDR1, FR2 and CDR2 ( Figure 5E ), similar to the result using the entire dataset ( Figure 4E ).

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