just missed significancep = 0.057
When pooling across both sexes, there were no differences between NGF and saline before injection (PD85 and 90: D = 0.197 and 0.047), but lower PPT at the injection site 1 day after NGF (PD86, PD91) with medium to large effect sizes ( D = 0.616, 0.634) that just missed significance vs. the saline controls ( p = 0.057 and 0.051) (Table 4 , top).