Incidence of patient-reported fatigue developing on palbociclib and endocrine therapy for advanced HR+ HER2- breast cancer.

Physical activity There was a statistical trend for lower levels of patient-reported physical activity at baseline predicting the emergence of fatigue ( P =.09, Supplementary Figure S1G ); treatment-emergent fatigue was observed more commonly in patients reporting the lowest tertile of physical activity versus those in the higher 2 tertiles combined (50% of 14 vs 20% of 61, respectively, P =.07).

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