Predictive Modeling of Pharmacokinetic Drug-Drug and Herb-Drug Interactions in Oncology: Insights From PBPK Studies.

Int J Toxicol · 2025 · PMC12397550 · PMID 40499171

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highly significantno p-value reported

The study shows a highly significant induction of CYP3A4, increasing hepatic clearance as high as 371% with moderate induction of CYP2B6, CYP2C8, and CYP2C9.

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