PYM1 limits non-canonical Exon Junction Complex occupancy in a gene architecture dependent manner to tune mRNA expression.

Nat Commun · 2025 · PMC12398555 · PMID 40885765

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highly significantno p-value reported

Strikingly, when single-exon mRNAs are compared as a group to multi-exon mRNAs, a highly significant enrichment of MAGOH E117R over MAGOH WT EJC footprints is observed on these unspliced mRNAs (Fig. 4a ).

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