Sleep, pericyte subtypes and cognitive decline in adults with and without Alzheimer's disease.

In secondary analyses of the small number of participants with snRNAseq data, at least one pericyte nucleus, and measurement of ante-mortem sleep fragmentation ( n = 56), there was a positive trend between sleep fragmentation and the proportion of M-pericyte nuclei that was nevertheless concordant in direction with the results seen in our bulk RNAseq data (estimate = +5.32 × 10 −1 , SE=+4.12 × 10 −1 , P = 0.2; Supplementary Fig. 9A ).

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