Combined neoadjuvant chemotherapy and immunotherapy in a hepatitis B virus-positive patient with locally advanced rectal adenocarcinoma: a case report and literature review.

Front Oncol · 2025 · PMC12404937 · PMID 40909950

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an increasing trendno p-value reported

In China, for example, more than 270,000 new cases and approximately 130,000 deaths were reported in 2020; notably, there is an increasing trend of onset at younger ages ( 2 , 3 ).

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