Impact of ethanol as a vehicle for water-insoluble pollutants in BEAS-2B cell toxicity assays.

Toxicol Mech Methods · 2025 · PMC12410134 · PMID 40728149

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hedged sentences

0.0010

closest p · 0.0× alpha

0.0660

boldest claim

The sentences

highly significantp < 0.001actually significant

Statistical analyses confirmed that while increasing ethanol caused highly significant changes in IL-8 levels ( p < 0.001), there were no differences between any HFHC-treated group and the corresponding ethanol-only VC at the same dose.

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narrowly missed statistical significancep = 0.066so close (0.05 < p ≤ 0.1)

Notably, two of the HFHC solvents (Calypsolv and EcoSolv) showed IL-8 dose–response curves strongly resembling ethanol’s pattern ( r ≈ 0.93), although correlations narrowly missed statistical significance ( p = 0.066), indicating a highly similar, though not conclusively identical, inflammatory response.

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