Green ultrasound‑assisted deep eutectic solvent extraction of flavonoid enzyme inhibitors from <i>Blumea aromatica</i>: process optimization, characterization, and mechanistic insights into <i>α</i>‑glucosidase and tyrosinase inhibition.

J Enzyme Inhib Med Chem · 2025 · PMC12412317 · PMID 40905571

Europe PMC DOI

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closest p · 0.0× alpha

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highly significantP < 0.0001actually significant

Analysis of variance of the regression model Multiple quadratic regression on the data yielded the following model: (3) Y = 2.94 + 0.2539 A + 0.1618 B + 0.0904 C + 0.0447 AB − 0.0230 AC + 0.0473 BC − 0.2315 A 2 − 0.0812 B 2 − 0.1554 C 2 Analysis of variance ( Table 4 ) shows that the model is highly significant ( P < 0.0001) with a non-significant lack-of-fit term ( P = 0.7481).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Green ultrasound‑assisted deep eutectic solvent extraction of flavonoid enzyme inhibitors from &lt;i&gt;Blumea aromatica&lt;/i&gt;: process optimization, characterization, and mechanistic insights into &lt;i&gt;α&lt;/i&gt;‑glucosidase and tyrosinase inhibition.

The sentences

Green ultrasound‑assisted deep eutectic solvent extraction of flavonoid enzyme inhibitors from <i>Blumea aromatica</i>: process optimization, characterization, and mechanistic insights into <i>α</i>‑glucosidase and tyrosinase inhibition.