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Proteomic profiling and scRNA sequencing identify signatures associated with <i>Helicobacter pylori</i> infection and risk of developing gastric cancer.

Cancer Biol Med · 2025 · PMC12418267 · PMID 40923140

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an increasing trendno p-value reported
pylori infection was shown to upregulate markers, such as OLFM4 and ENO1 , which exhibit an increasing trend from normal gastric tissue-to-IM, then to malignancy, thereby identifying key molecular events driving gastric carcinogenesis via H. pylori .

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