VP3.15, a dual GSK-3β/PDE7 inhibitor, reduces glioblastoma tumor growth though changes in the tumor microenvironment in a PTEN wild-type context.

Indeed, there is a highly significant correlation between the expression of LGALS9 (the gene encoding Gal9) and CD68 (a classical marker of GB macrophages) expression in patient samples from two distinct glioma cohorts ( Fig.

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