MskAge-An Epigenetic Biomarker of Musculoskeletal Age Derived From a Genetic Algorithm Islands Model.

Aging Cell · 2025 · PMC12419849 · PMID 40538142

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Lesioned cartilage exhibits significant Musculoskeletal Age acceleration in the hip (4.029 years, FDR = 0.003) and borderline significant Musculoskeletal Age acceleration in the knee (3.16 years, FDR = 0.067) relative to preserved non‐OA controls (Figure 6A,B ; Table S2 ).

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