Endoglin mediates the tumor- and metastasis-promoting traits of stromal myofibroblasts in human breast carcinomas.

In contrast, we observed a significant increase in tumor budding, indicative of a group of invading tumor cells and an increasing trend in lung metastasis in mice bearing tumors containing TGF‐β1‐expressing exp‐CAF2‐shENG‐2 cells (Fig. 4E,F ).

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