Barely Significant
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Low fT3/fT4 ratio as a proxy for muscle wasting in patients with advanced non-small cell lung cancer treated with pembrolizumab.

Front Oncol · 2025 · PMC12421168 · PMID 40936692

Europe PMCDOI
1
hedged sentence
0.0910
closest p · 1.8× alpha
0.0910
boldest claim

The sentences

a trend toward significancep = 0.091so close (0.05 < p ≤ 0.1)
When ECOG PS was accounted for as a confounding variable, the association between the fT3/fT4 ratio and muscle wasting demonstrated a trend toward significance (p = 0.091). fT3/fT4 ratio threshold, subgroup and survival analyses To further explore this relationship, ROC analysis was performed, which identified 2.84 as the optimal fT3/fT4 ratio threshold for distinguishing between low- and high-risk classifications for muscle depletion with the highest predictive accuracy.

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