Global, regional, and national burdens of five main digestive system cancers in adolescents and young adults from 1990 to 2021 based on the Global Burden of Disease Study 2021: A cross-sectional study.

PLoS One · 2025 · PMC12422433 · PMID 40929117

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a decreasing trendno p-value reported

an increasing trendno p-value reported

Results Globally, the ASIR (AAPC: 0.37) of AYAs with colorectal cancer (CRC) showed an increasing trend, whereas the ASIR of AYAs with esophageal cancer (EC), gastric cancer (GC), pancreatic cancer (PC), and liver cancer (LC) showed a decreasing trend.

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