<i>Lactobacillus salivarius</i> extracellular vesicles enhance gut and liver function in MAFLD.

Notably, no significant differences were detected in protein levels of PPARγ and SREBP1 in the in vivo and in vitro models, although a decreasing trend in SREBP1 protein levels was noted in LsEVs-treated mice ( Figures 6b, c ). 3.6 LsEVs alleviate MAFLD by protecting gut barrier integrity Research has shown that the functionality of the intestinal barrier is impaired in both mice and individuals suffering from fatty liver disease.

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